[ BBB ]
BBB & Drug Permeability Assessment
Does a candidate cross the barrier, or change its function?
BBB · Tissue schematic
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Conceptual view of brain endothelial cells, tight junctions, a pericyte and astrocytes around a capillary. Not an experimental image or an exact chip layout.
Study approach
- Define the transport or barrier question, candidate conditions and reference comparisons.
- Select the barrier model and establish baseline integrity measurements before treatment.
- Plan sampling across the barrier alongside electrical or imaging readouts suited to the model.
- Interpret transport alongside barrier condition, so changes in passage can be evaluated in their biological context.
- STUDY OUTPUT
- A transport or permeability comparison with barrier measurements, controls and model context.